{"id":2000,"date":"2018-07-31T09:52:50","date_gmt":"2018-07-31T08:52:50","guid":{"rendered":"https:\/\/ibb.uab.cat\/?p=2000"},"modified":"2018-10-31T10:25:19","modified_gmt":"2018-10-31T09:25:19","slug":"dr-a-villaverde-surface-bound-gradient-deposition-of-protein-nanoparticles-for-cell-motility-studies","status":"publish","type":"post","link":"https:\/\/ibb.uab.cat\/index.php\/2018\/07\/31\/dr-a-villaverde-surface-bound-gradient-deposition-of-protein-nanoparticles-for-cell-motility-studies\/","title":{"rendered":"Dr. A. Villaverde: Surface-Bound Gradient Deposition of Protein Nanoparticles for Cell Motility Studies"},"content":{"rendered":"<h2>\u00a0<\/h2>\n<h2 id=\"Abstract\" style=\"text-align: justify;\">Abstract<img loading=\"lazy\" class=\"size-full wp-image-2002 alignright\" src=\"https:\/\/ibb.uab.cat\/wp-content\/uploads\/am-2018-06821a_0008.gif\" alt=\"\" width=\"500\" height=\"226\" \/><\/h2>\n<div id=\"abstractBox\">\n<p style=\"text-align: justify;\">\u00a0<\/p>\n<p class=\"articleBody_abstractText\" style=\"text-align: justify;\">A versatile\u00a0evaporation-assisted methodology based on the coffee-drop effect is described to deposit nanoparticles on surfaces, obtaining for the first time patterned gradients of protein nanoparticles (pNPs) by using a simple custom-made device. Fully controllable patterns with specific periodicities consisting of stripes with different widths and distinct nanoparticle concentration as well as\u00a0gradients can be produced over large areas (\u223c10 cm<sup>2<\/sup>) in a fast (up to 10 mm<sup>2<\/sup>\/min), reproducible, and cost-effective manner using an operational protocol optimized by an evolutionary algorithm. The developed method opens the possibility to decorate surfaces \u201ca-la-carte\u201d with pNPs enabling different categories of high-throughput studies on cell motility.<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<p><a href=\"https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/acsami.8b06821\" target=\"_blank\" rel=\"noopener\">https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/acsami.8b06821<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0 Abstract \u00a0 A versatile\u00a0evaporation-assisted methodology based on the coffee-drop effect is described to deposit nanoparticles on surfaces, obtaining for the first time patterned gradients of protein nanoparticles (pNPs) by using a simple custom-made device. Fully controllable patterns with specific periodicities consisting of stripes with different widths and distinct nanoparticle concentration as well as\u00a0gradients can [&hellip;]<\/p>\n","protected":false},"author":65,"featured_media":2001,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[4],"tags":[],"_links":{"self":[{"href":"https:\/\/ibb.uab.cat\/index.php\/wp-json\/wp\/v2\/posts\/2000"}],"collection":[{"href":"https:\/\/ibb.uab.cat\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ibb.uab.cat\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ibb.uab.cat\/index.php\/wp-json\/wp\/v2\/users\/65"}],"replies":[{"embeddable":true,"href":"https:\/\/ibb.uab.cat\/index.php\/wp-json\/wp\/v2\/comments?post=2000"}],"version-history":[{"count":2,"href":"https:\/\/ibb.uab.cat\/index.php\/wp-json\/wp\/v2\/posts\/2000\/revisions"}],"predecessor-version":[{"id":2004,"href":"https:\/\/ibb.uab.cat\/index.php\/wp-json\/wp\/v2\/posts\/2000\/revisions\/2004"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ibb.uab.cat\/index.php\/wp-json\/wp\/v2\/media\/2001"}],"wp:attachment":[{"href":"https:\/\/ibb.uab.cat\/index.php\/wp-json\/wp\/v2\/media?parent=2000"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ibb.uab.cat\/index.php\/wp-json\/wp\/v2\/categories?post=2000"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ibb.uab.cat\/index.php\/wp-json\/wp\/v2\/tags?post=2000"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}