antibacTR is designed to help in identifying potential antimicrobial drug targets on Gram-negative bacteria. Please start by selecting the proteomes of interest. Proteins will be ranked according to a set of different criteria listed below. Each criterium has an associated weight factor, which modifies its influence in the final ranking. If a protein is similar to a known drug target or virulence factor, the corresponding link will be shown.

For detailed information please check the available documentation.
You may also hover your mouse over table headers to access a brief explanation.

Select proteomes of interest

Option/Command click for multiple choice

Top ranks to display:

Further options

Fine-tune scoring weights
Weight values are relative to each other, range is not defined.
If you wish to ignore a specific ranking parameter, a weight of 0 (zero) can be applied.

Essential GN-Conservation Strain-Conservation Toxicity Paralogs

BLAST Filter
If you are interested in specific proteins, please insert their sequences in FASTA format in the box below.
The output will be restricted to related BLAST hits.

BLAST E-value threshold:

This project has been supported by funding under the Seventh Research Framework Programme of the European Union (ref. HEALTH-F3-2009-223101, AntiPathoGN) and the Spanish Ministry for Science and Innovation (BFU2010-17199).

If you find this server useful please cite:
antibacTR: dynamic antibacterial-drug-target ranking integrating comparative genomics, structural analysis and experimental annotation.
Panjkovich A, Gibert I, Daura X.
BMC Genomics. 2014 Jan 17; 15:36.